PRMT5-IN-9

PRMT5-IN-9 is a novel PRMT5 inhibitor for researching cancer, with an IC50 of 0.01 μM.

Product Specifications

CAS Number

[2691869-52-8]

UNSPSC

12352005

Target

Histone Methyltransferase

Type

Reference compound

Related Pathways

Epigenetics

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/prmt5-in-9.html

Solubility

10 mM in DMSO

Smiles

CC1=CC2=C(N=C1N)C=CC(C(N([C@@H]3CCCC4=C3NN=C4)CC5=CC=C(C=N5)C(F)(F)F)=O)=C2

Molecular Formula

C25H23F3N6O

Molecular Weight

480.48

References & Citations

[1]Allen JR, et al. Novel PRMT5 Inhibitors. WO2021163344A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PRMT5

Curated Selection

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