PCSK9-IN-2
Product Specifications
CAS Number
2099167-44-7
UNSPSC Description
PCSK9-IN-2 is a novel small molecule inhibitor of PCSK9-LDLR protein–protein interaction (PPI) with an IC50 value of 7.57 μM.
Target Antigen
PCSK9
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/pcsk9-in-2.html
Solubility
10 mM in DMSO
Smiles
O=C1NCCCC[C@H]1N[C@@H]2CC(N(C2=O)C3=CC=C(C=C3)N4C(C[C@H](C4=O)N[C@@H]5CCCCNC5=O)=O)=O
Molecular Weight
524.57
References & Citations
[1]Sun H, et al. Discovery of Novel Small Molecule Inhibitors Disrupting the PCSK9-LDLR Interaction. J Chem Inf Model. 2021 Oct 25;61(10):5269-5279.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported
Frequently Asked Questions
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