ZXH-4-137
ZXH-4-137 is a potent and selective CRBN degrader (PROTAC) .
Product Specifications
CAS Number
2711006-74-3
UNSPSC
12352005
Target
PROTACs
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/zxh-4-137.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=C(OCCCCCCCCCCC(N[C@@H](C(C)(C)C)C(N3[C@@H](C[C@H](C3)O)C(N[C@H](C4=CC=C(C5=C(N=CS5)C)C=C4)C)=O)=O)=O)C=CC=C2C(N1C6C(NC(CC6)=O)=O)=O
Molecular Formula
C47H60N6O9S
Molecular Weight
885.08
References & Citations
[1]Powell CE, et al. Selective degradation-inducing probes for studying cereblon (CRBN) biology. RSC Med Chem. 2021 Jul 6;12 (8) :1381-1390.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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