Corixetan
Corixetan is a highly efficient thorium chelator. Corixetan can efficiently complex Th-227 with sufficient in vivo stability[1].
Product Specifications
CAS Number
1952359-26-0
UNSPSC
12352203
Target
ADC Payload
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/corixetan.html
Solubility
10 mM in DMSO
Smiles
O=C(O)CCC(NC1=CC=C(CC(CN(CCNC(C(C=CN2C)=C(O)C2=O)=O)CCNC(C(C=CN3C)=C(O)C3=O)=O)CN(CCNC(C(C=CN4C)=C(O)C4=O)=O)CCNC(C(C=CN5C)=C(O)C5=O)=O)C=C1)=O
Molecular Formula
C50H61N11O15
Molecular Weight
1056.08
References & Citations
[1]Ramdahl T, et al. An efficient chelator for complexation of thorium-227. Bioorg Med Chem Lett. 2016 Sep 1;26 (17) :4318-21.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Traditional Cytotoxic Agents
Frequently Asked Questions
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