Nezulcitinib
Nezulcitinib (TD-0903) is an inhaled and lung-selective pan-Janus kinase (JAK) inhibitor. Nezulcitinib can be used for the research of COVID-19 associated acute lung injury and impaired oxygenation[1][2].
Product Specifications
CAS Number
2412496-23-0
Product Name Alternative
TD-0903
UNSPSC
12352005
Target
JAK
Type
Reference compound
Related Pathways
Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Applications
COVID-19-anti-virus
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/nezulcitinib.html
Solubility
10 mM in DMSO
Smiles
O=C(N1CC(C1)N(C)C)[C@@H]2CC3=C(CN2C(C)C)N=C(C4=NNC5=CC(C6=C(C=C(C=C6)O)CC)=CC=C45)N3
Molecular Formula
C30H37N7O2
Molecular Weight
527.66
References & Citations
[1]Theravance's nezulcitinib fails to meet Phase II goals in Covid-19|[2]Theravance biopharma, inc. Announces top-line results from phase 2 study of nezulcitinib in patients hospitalized with acute lung injury due to COVID-19
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
JAK
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![RSPO1 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI11A9]](https://cdn.genprice.uk/products/937/68dd1b7b061270361ea1c365/imageurl/ta804626am.webp)
TA804626AM 100 µL
RSPO1 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI11A9]
Sign In for Pricing
View Details ![Claudin 7 Recombinant Mouse Monoclonal Antibody [6-G3-R]](https://cdn.genprice.uk/products/992/68dd1c8a061270361ea810e7/imageurl/ha601346.webp)
HA601346 100 µL
Claudin 7 Recombinant Mouse Monoclonal Antibody [6-G3-R]
Sign In for Pricing
View Details 
TP762288 50 µg
TIF1 alpha (TRIM24) (NM_003852) Human Recombinant Protein
Sign In for Pricing
View Details 
TRC-F597790-500MG 500 mg
Fluorescent Brightener ER-II, 1-(2-Cyanostyryl)-4-(4-cyanostyryl)benzene
Sign In for Pricing
View Details 
![GOLPH2 (GOLM1) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI4B3]](https://cdn.genprice.uk/products/937/68dd1b6d061270361ea16f94/imageurl/ta504114am.webp)
TA504114AM 100 µL
GOLPH2 (GOLM1) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI4B3]
Sign In for Pricing
View Details