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Odatroltide

Odatroltide (LT3001; DHDMIQK (KAP) ) is a P-selectin inhibitor. Odatroltide is a peptide molecule comprising a tripeptide Pro-Ala-Lys (PAK) and an (S) -6,7-dihydroxy-1,1-dimethyl-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid domain. Odatroltide can restore cerebral blood flow, scavenge free radicals, and inhibit leukocyte migration. Odatroltide possesses thrombolytic and anti-thrombotic activities[1][2].

Product Specifications

CAS Number

1639303-73-3

Product Name Alternative

LT3001; DHDMIQK (KAP)

UNSPSC

12352005

Target

P-selectin

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/odatroltide.html

Purity

97.39

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

CC1(C2=CC(O)=C(O)C=C2C[C@H](N1)C(N[C@H](C(O)=O)CCCCNC([C@H](CCCCN)NC([C@H](C)NC([C@@H]3CCCN3)=O)=O)=O)=O)C

Molecular Formula

C32H51N7O8

Molecular Weight

661.79

References & Citations

[1]Feng Q, et al. DHDMIQK (KAP) : a novel nano-delivery system of dihydroxyl-tetrahydro-isoquinoline-3-carboxylic acid and KPAK towards the thrombus. J Mater Chem B. 2016;4 (36) :5991-6003.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Scientific Category

Peptides

Clinical Information

Phase 2

Available Sizes

Frequently Asked Questions

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