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Ledaborbactam etzadroxil

Ledaborbactam etzadroxil (VNRX-7145) is an orally active Ambler class A, C, and D β-lactamase enzymes inhibitor[1].

Product Specifications

CAS Number

1842399-68-1

Product Name Alternative

VNRX-7145

UNSPSC

12352005

Target

Bacterial; Beta-lactamase

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/ledaborbactam-etzadroxil.html

Solubility

10 mM in DMSO

Smiles

CCC(CC)C(OCOC(C1=C2C(C[C@@H](B(O2)O)NC(CC)=O)=CC=C1)=O)=O

Molecular Formula

C19H26BNO7

Molecular Weight

391.22

References & Citations

[1]Robert E Trout, et al. Discovery of VNRX-7145 (VNRX-5236 Etzadroxil) : An Orally Bioavailable β-Lactamase Inhibitor for Enterobacterales Expressing Ambler Class A, C, and D Enzymes. J Med Chem. 2021 Jul 22;64 (14) :10155-10166.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 1

Available Sizes

Frequently Asked Questions

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