MTL-CEBPA
MTL-CEPBA is a small activating RNA targeting for upregulation of C/EBPα. MTL-CEPBA has anti-inflammatory and anti-cancer activity[1].
Product Specifications
CAS Number
2862057-05-2
Product Name Alternative
CEBPA-51
UNSPSC
12352208
Target
MicroRNA
Type
Oligonucleotides
Related Pathways
Epigenetics
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/mtl-cebpa.html
Purity
95.52
Solubility
10 mM in H2O
Smiles
[MTL-CEBPA]
Molecular Weight
13464.27
References & Citations
[1]Jiehua Zhou, et al. Anti-inflammatory Activity of MTL-CEBPA, a Small Activating RNA Drug, in LPS-Stimulated Monocytes and Humanized Mice. Mol Ther. 2019 May 8;27 (5) :999-1016.|[2]Reebye V, Huang KW, Lin V, et al. Gene activation of CEBPA using saRNA: preclinical studies of the first in human saRNA drug candidate for liver cancer. Oncogene. 2018;37 (24) :3216-3228. |[3]Combination therapies comprising C/EBPα-targeted short-activating RNA (saRNA) . WO2022229644A1
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Oligonucleotides
Clinical Information
Phase 2
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