RG-101

RG-101 is a hepatocyte targeted N-acetylgalactosamine conjugated oligonucleotide that antagonises miR-122. miR-122 is an important host factor for hepatitis C virus (HCV) replication[1].

Product Specifications

CAS Number

1929655-04-8

Product Name Alternative

Temavirsen

UNSPSC

12352208

Target

HCV; MicroRNA

Type

Oligonucleotides

Related Pathways

Anti-infection; Epigenetics

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/rg-101.html

Solubility

10 mM in H2O

Smiles

[RG-101]

Molecular Formula

C295H410N78Na19O146P19S17

Molecular Weight

8537.6

References & Citations

[1]Meike H van der Ree, et al. Safety, tolerability, and antiviral effect of RG-101 in patients with chronic hepatitis C: a phase 1B, double-blind, randomised controlled trial. Lancet. 2017 Feb 18;389 (10070) :709-717.