Revusiran
Revusiran (ALN-TTRSC) is a 1st-generation short interfering RNA, which directed against transthyretin (TTR) mRNA. Revusiran can be used for transthyretin (TTR) -mediated amyloidosis research[1].
Product Specifications
CAS Number
[1438322-82-7]
Product Name Alternative
ALN-TTRSC
UNSPSC
12352208
Target
Small Interfering RNA (siRNA) ; Transthyretin (TTR)
Type
Oligonucleotides
Related Pathways
Epigenetics; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/revusiran.html
Solubility
10 mM in H2O
Smiles
[Revusiran]
Molecular Weight
16121.00
References & Citations
[1]Jessica E Sutherland, et al. Nonclinical Safety Profile of Revusiran, a 1st-Generation GalNAc-siRNA Conjugate for Treatment of Hereditary Transthyretin-Mediated Amyloidosis. Nucleic Acid Ther. 2020 Feb;30 (1) :33-49.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
Phase 3
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