IONIS-DNM2-2.5Rx (sodium)
IONIS-DNM2-2.5Rx sodium is an antisense agent targeting dynamin 2, and has the potential for the research of centronuclear myopathy (CNM) [1].
Product Specifications
Product Name Alternative
DYM101 (sodium)
UNSPSC
12352208
Target
Dynamin
Type
Oligonucleotides
Related Pathways
Cytoskeleton
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/ionis-dnm2-2-5rx-sodium.html
Purity
97.46
Solubility
10 mM in H2O
Smiles
[IONIS-DNM2-2.5Rx(sodium)]
References & Citations
[1]Buono S, Ross JA, Tasfaout H, et al. Reducing dynamin 2 (DNM2) rescues DNM2-related dominant centronuclear myopathy. Proc Natl Acad Sci U S A. 2018;115 (43) :11066-11071.|[2]Tasfaout H, Buono S, Guo S, et al. Antisense oligonucleotide-mediated Dnm2 knockdown prevents and reverts myotubular myopathy in mice. Nat Commun. 2017;8:15661.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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