HIV-1 integrase inhibitor 9
HIV-1 integrase inhibitor 9 (compound 8a) is a potent HIV-1 RNase H inhibitor with an IC50 of 12.3 μM. HIV-1 integrase inhibitor 9 shows an antiviral activity[1].
Product Specifications
CAS Number
2709085-95-8
UNSPSC
12352005
Target
HIV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/hiv-1-integrase-inhibitor-9.html
Solubility
10 mM in DMSO
Smiles
OC1=C(C([N+]([O-])=O)=CC2=C1OC(C(C(NC3=CC(C(OC)=O)=C(C=C3)O)=O)=C2)=O)O
Molecular Formula
C18H12N2O10
Molecular Weight
416.30
References & Citations
[1]Dongwei Kang, et al. Discovery, optimization, and target identification of novel coumarin derivatives as HIV-1 reverse transcriptase-associated ribonuclease H inhibitors. Eur J Med Chem. 2021 Dec 5;225:113769.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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