HIV-1 integrase inhibitor 9
HIV-1 integrase inhibitor 9 (compound 8a) is a potent HIV-1 RNase H inhibitor with an IC50 of 12.3 μM. HIV-1 integrase inhibitor 9 shows an antiviral activity[1].
Product Specifications
CAS Number
2709085-95-8
UNSPSC
12352005
Target
HIV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/hiv-1-integrase-inhibitor-9.html
Solubility
10 mM in DMSO
Smiles
OC1=C(C([N+]([O-])=O)=CC2=C1OC(C(C(NC3=CC(C(OC)=O)=C(C=C3)O)=O)=C2)=O)O
Molecular Formula
C18H12N2O10
Molecular Weight
416.30
References & Citations
[1]Dongwei Kang, et al. Discovery, optimization, and target identification of novel coumarin derivatives as HIV-1 reverse transcriptase-associated ribonuclease H inhibitors. Eur J Med Chem. 2021 Dec 5;225:113769.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
LC400896 20 µg
Entactin (NID1) (NM_002508) Human Over-expression Lysate
Sign In for Pricing
View Details 
