(1S,3R)-GNE-502
Product Specifications
UNSPSC Description
(1S,3R)-GNE-502 (compound 179) is a potent ERα degrader with an EC50 value of 13 nM against ERα in MCF7 HCS. (1S,3R)-GNE-502 can be used to research cancer related with estrogen receptor[1].
Target Antigen
Estrogen Receptor/ERR
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/1s-3r-gne-502.html
Solubility
10 mM in DMSO
Smiles
C[C@@H]1CC(C2=CC=CC=C2N3)=C3[C@H](C4=CC=C(C=C4)OCCN5CC(C5)CF)N1S(=O)(C)=O
Molecular Weight
471.59
References & Citations
[1]Simon Charles Goodacre, et al. Tetrahydro-Pyrido[3,4-b]Indole Estrogen Receptor Modulators And Uses Thereof. WO2016097072A1.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-132294A/1S-3R-GNE-502-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-132294A/
Clinical Information
No Development Reported
CAS Number
1953134-15-0
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![MSMB Mouse Monoclonal Antibody [Clone ID: OTI2A3]](https://cdn.genprice.uk/genprice/genprice2.png)
