Fmoc-N-amido-PEG5-azide
Product Specifications
UNSPSC Description
Fmoc-N-amido-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Fmoc-N-amido-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Target Antigen
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fmoc-n-amido-peg5-azide.html
Solubility
10 mM in DMSO
Smiles
O=C(NCCOCCOCCOCCOCCOCCN=[N+]=[N-])OCC1C2=C(C3=C1C=CC=C3)C=CC=C2
Molecular Weight
528.60
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-132111/Fmoc-N-amido-PEG5-azide-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-132111/
Clinical Information
No Development Reported
CAS Number
2924480-17-9
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1471736-01 0.02 mg (E-Coli)
Recombinant Pseudomonas syringae pv. tomato Probable chorismate--pyruvate lyase (ubiC)
Ask
View Details MBS1471736-02 0.1 mg (E-Coli)
Recombinant Pseudomonas syringae pv. tomato Probable chorismate--pyruvate lyase (ubiC)
Ask
View Details 
MBS1471736-03 0.02 mg (Yeast)
Recombinant Pseudomonas syringae pv. tomato Probable chorismate--pyruvate lyase (ubiC)
Ask
View Details MBS1471736-04 0.1 mg (Yeast)
Recombinant Pseudomonas syringae pv. tomato Probable chorismate--pyruvate lyase (ubiC)
Ask
View Details MBS1471736-05 0.02 mg (Baculovirus)
Recombinant Pseudomonas syringae pv. tomato Probable chorismate--pyruvate lyase (ubiC)
Ask
View Details MBS1471736-06 0.02 mg (Mammalian-Cell)
Recombinant Pseudomonas syringae pv. tomato Probable chorismate--pyruvate lyase (ubiC)
Ask
View Details