Fmoc-N-amido-PEG5-azide
Fmoc-N-amido-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Fmoc-N-amido-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Product Specifications
CAS Number
[2924480-17-9]
UNSPSC
12352005
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fmoc-n-amido-peg5-azide.html
Solubility
10 mM in DMSO
Smiles
O=C(NCCOCCOCCOCCOCCOCCN=[N+]=[N-])OCC1C2=C(C3=C1C=CC=C3)C=CC=C2
Molecular Formula
C27H36N4O7
Molecular Weight
528.60
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers
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