Antineoplastic agent-1
Antineoplastic agent-1 is an alkylating agent and a genotoxic agent that can induce DNA damage. Antineoplastic agent-1 can lead to irreversible damage and progressive death of liver cells due to necroptosis and apoptosis. Antineoplastic agent-1 can cause alkylation damage to hematopoietic cells and stromal cells in the bone marrow. Antineoplastic agent-1 can be used in tumor research[1][2].
Product Specifications
CAS Number
738-99-8
UNSPSC
12352005
Target
Apoptosis; Necroptosis
Type
Reference compound
Related Pathways
Apoptosis
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/antineoplastic-agent-1.html
Smiles
O=P(N1CC1)(N2CCN(P(N3CC3)(N4CC4)=O)CC2)N5CC5
Molecular Formula
C12H24N6O2P2
Molecular Weight
346.31
References & Citations
[1]Factor VM, Radaeva SA, Thorgeirsson SS. Origin and fate of oval cells in dipin-induced hepatocarcinogenesis in the mouse. Am J Pathol. 1994 Aug;145 (2) :409-22.|[2]Jensen MR, et al. Regulation of cyclin G1 during murine hepatic regeneration following Dipin-induced DNA damage. Hepatology. 1998 Aug;28 (2) :537-46.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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