BRL-15572 (hydrochloride)
BRL-15572 hydrochloride is a selective antagonist of h5-HT1D, displays high affinity for h5-HT1D receptors. BRL-15572 hydrochloride could be useful pharmacological agents to characterise 5-HT1D receptor mediated responses[1].
Product Specifications
CAS Number
1173022-77-9
UNSPSC
12352005
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/brl-15572-hydrochloride.html
Solubility
10 mM in DMSO
Smiles
OC(C(C1=CC=CC=C1)C2=CC=CC=C2)CN3CCN(C4=CC=CC(Cl)=C4)CC3.[H]Cl
Molecular Formula
C25H28Cl2N2O
Molecular Weight
443.41
References & Citations
[1]Price GW, et, al. SB-216641 and BRL-15572--compounds to pharmacologically discriminate h5-HT1B and h5-HT1D receptors. Naunyn Schmiedebergs Arch Pharmacol. 1997 Sep; 356 (3) : 312-20.|[2]Geovanna NQ, et, al. Antinociceptive effect of (-) -epicatechin in inflammatory and neuropathic pain in rats. Behav Pharmacol. 2018 Apr; 29 (2 and 3-Spec Issue) : 270-279.|[3]Hagan JJ, et, al. Stimulation of 5-HT1B receptors causes hypothermia in the guinea pig. Eur J Pharmacol. 1997 Jul 23; 331 (2-3) : 169-74.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT1 Receptor; mLAG-3
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