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MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH (GMP)

MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH GMP is a GMP grade MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH. MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Product Specifications

CAS Number

1599440-25-1

UNSPSC

12352005

Hazard Statement

H302-H315-H319

Target

ADC Linker

Type

GMP Small Molecules

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mc-gly-gly-phe-gly-nh-ch2-o-ch2cooh-gmp.html

Solubility

10 mM in DMSO

Smiles

OC(COCNC(CNC([C@@H](NC(CNC(CNC(CCCCCN1C(C=CC1=O)=O)=O)=O)=O)CC2=CC=CC=C2)=O)=O)=O

Molecular Formula

C28H36N6O10

Molecular Weight

616.62

Precautions

P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501

References & Citations

[1]Masuda, Takeshi, et al. Conjugué anticorps-médicament. WO2014057687A1.

Shipping Conditions

Room temperature

Scientific Category

GMP Small Molecules

Clinical Information

No Development Reported

Frequently Asked Questions

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