LSD1/HDAC6-IN-1

LSD1/HDAC6-IN-1 is an orally active dual inhibitor of lysine specific demethylase 1 (LSD1) /Histone deacetylase 6 (HDAC6), with anti-tumor activity. LSD1/HDAC6-IN-1 can be used for the research of multiple myeloma (MM) [1].

Product Specifications

CAS Number

[2738306-38-0]

UNSPSC

12352005

Target

HDAC; Histone Demethylase

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/lsd1-hdac6-in-1.html

Solubility

10 mM in DMSO

Smiles

ONC(C(C=C1)=CC=C1CCCN(CC2)CCC2CN[C@@H]3[C@@H](C4=CC=CC=C4)C3)=O

Molecular Formula

C25H33N3O2

Molecular Weight

407.55

References & Citations

[1]M Naveen Sadhu, et al. Novel dual LSD1/HDAC6 inhibitors for the treatment of multiple myeloma. Bioorg Med Chem Lett. 2020 Dec 24;34:127763.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

HDAC6; KDM1/LSD1

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