5-HT3 antagonist 4
5-HT3 antagonist 4 is a 5-HT3 receptor (5HT3R) antagonist. 5-HT3 antagonist 4 prevents diabetes-induced depressive phenotypes in mice[1].
Product Specifications
CAS Number
930478-88-9
UNSPSC
12352005
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/5-ht3-antagonist-4.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=NC2=CC=CC=C2N=C1)NC3=CC=CC(Cl)=C3C
Molecular Formula
C16H12ClN3O
Molecular Weight
297.74
References & Citations
[1]Deepali Gupta, et al. A novel 5HT3 antagonist 4i (N- (3-chloro-2-methylphenyl) quinoxalin-2-carboxamide) prevents diabetes-induced depressive phenotypes in mice: Modulation of serotonergic system. Behav Brain Res. 2016 Jan 15;297:41-50.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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