Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

SFTX-3.3

SFTX-3.3 is a Ca2+ channel antagonist with IC50s of approximately 0.24 mM and 0.70 mM against P-type and N-type channels[1][2].

Product Specifications

CAS Number

141997-14-0

UNSPSC

12352211

Target

Calcium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/sftx-3-3.html

Solubility

10 mM in DMSO

Smiles

O=C(NCCCNCCCN)[C@@H](N)CCCNC(N)=N

Molecular Formula

C12H29N7O

Molecular Weight

287.40

References & Citations

[1]Maria Elisa Calcagnotto, et al. An examination of calcium current function on heterotopic neurons in hippocampal slices from rats exposed to methylazoxymethanol. Epilepsia. 2003 Mar;44 (3) :315-21.|[2]T M Norris, et al. Block of high-threshold calcium channels by the synthetic polyamines sFTX-3.3 and FTX-3.3. Mol Pharmacol. 1996 Oct;50 (4) :939-46.|[3]M Fatehi, et al. Polyamine FTX-3.3 and polyamine amide sFTX-3.3 inhibit presynaptic calcium currents and acetylcholine release at mouse motor nerve terminals. Neuropharmacology. 1997 Feb;36 (2) :185-94.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

N-type calcium channel; P/Q-type calcium channel

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

IMP5 Rabbit Polyclonal Antibody (Biotin)
orb2107909 100 µL

IMP5 Rabbit Polyclonal Antibody (Biotin)

Sign In for Pricing
View Details
Phospho-BRCA1 (Ser1189) Polyclonal Antibody, AbBy Fluor™ 594 Conjugated
bs-5221R-BF594 100 µL

Phospho-BRCA1 (Ser1189) Polyclonal Antibody, AbBy Fluor™ 594 Conjugated

Sign In for Pricing
View Details
LDHA Recombinant Antibody, Cy5 Conjugated
bsm-62875R-Cy5 100 µL

LDHA Recombinant Antibody, Cy5 Conjugated

Sign In for Pricing
View Details
TMEM196 Human shRNA Plasmid Kit (Locus ID 256130)
TR318172 1 Kit

TMEM196 Human shRNA Plasmid Kit (Locus ID 256130)

Sign In for Pricing
View Details
Rabbit Polyclonal PDLIM4 Antibody [mFluor Violet 450 SE]
NBP2-98063MFV450 0.1 mL

Rabbit Polyclonal PDLIM4 Antibody [mFluor Violet 450 SE]

Sign In for Pricing
View Details
Mouse FMS-like tyrosine kinase 3 (FLT3) ELISA Kit
RK06103 96 Tests

Mouse FMS-like tyrosine kinase 3 (FLT3) ELISA Kit

Sign In for Pricing
View Details