Pomalidomide 4'-alkylC3-acid

Pomalidomide 4'-alkylC3-acid is the E3 ligase ligand-linker conjugate used in the recruitment of CRBN protein. Pomalidomide 4'-alkylC3-acid can be used to synthesize PROTACs[1].

Product Specifications

CAS Number

[2225940-47-4]

UNSPSC

12352005

Hazard Statement

H361

Target

E3 Ligase Ligand-Linker Conjugates

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/pomalidomide-4-alkylc3-acid.html

Purity

98.0

Solubility

10 mM in DMSO

Smiles

O=C(O)CCCNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O

Molecular Formula

C17H17N3O6

Molecular Weight

359.33

Precautions

H361

References & Citations

[1]Jing Liu, et al. Tropomyosin receptor kinase (trk) degradation compounds and methods of use. WO2020038415A1.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

More Discoveries

Explore Other Products

Browse additional items from our catalog

E38QA1070 100 µL

Alpha-galactosidase A Antibody

View Details

RC203195L2V 200 µL

STK40 (NM_032017) Human Tagged ORF Clone Lentiviral Particle

View Details

TU215191 1.0 mL

Olr418 3'UTR Luciferase Stable Cell Line

View Details

PV059570 500 ng

UPF3B Protein Vector (Human) (pPB-N-His)

View Details

SC315550 10 µg

CRELD1 (NM_001077415) Human Untagged Clone

View Details

YLD7328-01 50 µL

Rabbit anti-SOX2 Antibody

View Details