Pomalidomide 4'-alkylC3-acid

Pomalidomide 4'-alkylC3-acid is the E3 ligase ligand-linker conjugate used in the recruitment of CRBN protein. Pomalidomide 4'-alkylC3-acid can be used to synthesize PROTACs[1].

Product Specifications

CAS Number

[2225940-47-4]

UNSPSC

12352005

Hazard Statement

H361

Target

E3 Ligase Ligand-Linker Conjugates

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/pomalidomide-4-alkylc3-acid.html

Purity

98.0

Solubility

10 mM in DMSO

Smiles

O=C(O)CCCNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O

Molecular Formula

C17H17N3O6

Molecular Weight

359.33

Precautions

H361

References & Citations

[1]Jing Liu, et al. Tropomyosin receptor kinase (trk) degradation compounds and methods of use. WO2020038415A1.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

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