Pomalidomide 4'-alkylC3-acid

Pomalidomide 4'-alkylC3-acid is the E3 ligase ligand-linker conjugate used in the recruitment of CRBN protein. Pomalidomide 4'-alkylC3-acid can be used to synthesize PROTACs[1].

Product Specifications

CAS Number

[2225940-47-4]

UNSPSC

12352005

Hazard Statement

H361

Target

E3 Ligase Ligand-Linker Conjugates

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/pomalidomide-4-alkylc3-acid.html

Purity

98.0

Solubility

10 mM in DMSO

Smiles

O=C(O)CCCNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O

Molecular Formula

C17H17N3O6

Molecular Weight

359.33

Precautions

H361

References & Citations

[1]Jing Liu, et al. Tropomyosin receptor kinase (trk) degradation compounds and methods of use. WO2020038415A1.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

More Discoveries

Explore Other Products

Browse additional items from our catalog

TA368620 100 µL

Keratin 36 (KRT36) Rabbit Polyclonal Antibody

View Details

M2429-03-PE 100 µL

Matrix Metalloproteinase 14 (MT1-MMP, MMP-14, Collagenase-3) (PE) discontinued

View Details

PVT75270 2 µg

PCMV-DSC1-P2A-mCherry-Neo Plasmid

View Details

61313086 1.0 µg

LOC689425 3'UTR Lenti-reporter-Luc Vector

View Details

365527 200 µL

UPK2 (Uroplakin 2, UPII, Uroplakin II)

View Details

38473086 1.0 µg

Ranbp1 3'UTR Lenti-reporter-Luc Vector

View Details