2'-NH2-ATP
2'-NH2-ATP (2'-Amino-2'-deoxyadenosine-5'-triphosphate), an adenosine derivative, is a weak competitive inhibitor of ATP, with a Ki of 2.3 mM. 2'-NH2-ATP can be used in nucleic acid labeling[1][2][3].
Product Specifications
CAS Number
61468-88-0
Product Name Alternative
2'-Amino-2'-deoxyadenosine-5'-triphosphate
UNSPSC
12352005
Target
Biochemical Assay Reagents
Type
Reference compound
Related Pathways
Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/2-nh2-atp.html
Solubility
10 mM in DMSO
Smiles
OP(OP(OC[C@H]1O[C@@H](N2C3=NC=NC(N)=C3N=C2)[C@H](N)[C@@H]1O)(O)=O)(OP(O)(O)=O)=O
Molecular Formula
C10H17N6O12P3
Molecular Weight
506.20
References & Citations
[1]Armstrong VW, et, al. Interaction of substrate analogues with Escherichia coli DNA-dependent RNA polymerase. Eur J Biochem. 1976 Nov 1;70 (1) :33-8.|[2]Faylene A. L. KINETIC STUDIES ON WILD-TYPE AND MUTANT ESCHERICHIA COLICYTIDINE 5'-TRIPHOSPHATE SYNTHASES AND INHIBITOR DEVELOPMENT. Dalhousie University Halifax, Nova Scotia. 2008 Jul.|[3]Aström H, et, al. Acidity of secondary hydroxyls in ATP and adenosine analogues and the question of a 2',3'-hydrogen bond in ribonucleosides. J Am Chem Soc. 2004 Nov 17;126 (45) :14710-1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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