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Δ4-Dafachronic acid

Δ4-Dafachronic acid is an agonist of DAF-12 and a metabolite of cholesterol[1].

Product Specifications

CAS Number

[23017-97-2]

UNSPSC

12352211

Target

Drug Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/4-dafachronic-acid.html

Purity

96.0

Solubility

10 mM in DMSO|DMSO : ≥ 2.5mg/mL

Smiles

CC(C(O)=O)CCC[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])CCC4=CC(CC[C@]4(C)[C@@]3([H])CC[C@]12C)=O

Molecular Formula

C27H42O3

Molecular Weight

414.62

References & Citations

[1]Amie L T Romney, et al. Temperature-dependent vitamin D signaling regulates developmental trajectory associated with diapause in an annual killifish. Proc Natl Acad Sci U S A. 2018 Dec 11;115 (50) :12763-12768.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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