Cetirizine Impurity C

Cetirizine Impurity C is an impurity of Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist[1][2].

Product Specifications

CAS Number

[83881-59-8]

UNSPSC

12352005

Hazard Statement

H302-H312-H319-H335-H361-H400

Target

Histamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/cetirizine-impurity-c.html

Solubility

10 mM in DMSO

Smiles

O=C(O)COCCN1CCN(C(C2=CC=CC=C2Cl)C3=CC=CC=C3)CC1

Molecular Formula

C21H25ClN2O3

Molecular Weight

388.89

Precautions

P261-P264-P270-P271-P273-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P391-P403+P233-P405-P501

References & Citations

[1]Shih MY, et al. Influence of cetirizine and levocetirizine on two cytokines secretion in human airway epithelial cells. Allergy Asthma Proc. 2008 Sep-Oct;29 (5) :480-5.|[2]Shimizu T, et al. Cetirizine, an H1-receptor antagonist, suppresses the expression of macrophage migration inhibitory factor: its potential anti-inflammatory action. Clin Exp Allergy. 2004 Jan;34 (1) :103-9.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

H1 Receptor

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

bs-4136R-BF680 100 µL

MEF2D Polyclonal Antibody, AbBy Fluor™ 680 Conjugated

Ask

View Details

abx239148 100 µg

Ubiquitin-Associated Domain-Containing Protein 2 (UBAC2) Antibody

Ask

View Details

A12678-10 10 mg

His-Pro 10mg

Ask

View Details