JAK2/STAT3-IN-1
JAK2/STAT3-IN-1 (compound (S) -10a) is a potent GP130 inhibitor with an IC50 of 3.04 µM. JAK2/STAT3-IN-1 shows anti-tumor activity[1].
Product Specifications
CAS Number
2485758-50-5
UNSPSC
12352005
Target
Interleukin Related
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/jak2-stat3-in-1.html
Solubility
10 mM in DMSO
Smiles
O=C(N1N=C(C2=CC=C(C(F)(F)F)C=C2)C[C@H]1C3=CN(CC4=CC=C(OCCN5CCCCCC5)C=C4)C6=C3C=C(Br)C=C6)N
Molecular Formula
C34H35BrF3N5O2
Molecular Weight
682.57
References & Citations
[1]Song D, et al. Discovery of bazedoxifene analogues targeting glycoprotein 130. Eur J Med Chem. 2020 Aug 1;199:112375.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC401541-500 1x 500 µL
Calnexin (Endoplasmic Reticulum Marker) (CANX/1541), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
