Pomalidomide-amido-C3-piperazine-N-Boc
Pomalidomide-amido-C3-piperazine-N-Boc is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in the synthesis of PROTAC PD-1/PD-L1 degrader-1 (HY-131183) [1].
Product Specifications
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pomalidomide-amido-c3-piperazine-n-boc.html
Solubility
10 mM in DMSO
Smiles
O=C(CCCC(N1CCN(CC1)C(OC(C)(C)C)=O)=O)NC2=CC=CC(C(N3C(C(N4)=O)CCC4=O)=O)=C2C3=O
Molecular Formula
C27H33N5O8
Molecular Weight
555.58
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon
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