Chymase
Product Specifications
UNSPSC Description
Chymase is a protein-digester enzyme found primarily in mast cells (MC), fibroblasts, and vascular endothelial cells. Chymase is released into the extracellular stroma in the context of inflammatory signals, tissue injury and cellular stress. Chymase is also involved in angiotensin II (Ang II) production, which is used in cardiovascular disease studies[1].
Target Antigen
Angiotensin Receptor
Type
Enzyme
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/chymase.html
Solubility
10 mM in DMSO
Smiles
[Chymase]
References & Citations
[1]Ahmad S, et al. Chymase inhibitors for the treatment of cardiac diseases: a patent review (2010-2018). Expert Opin Ther Pat. 2018 Nov;28(11):755-764.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-131162/Chymase-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-131162/
Clinical Information
No Development Reported
CAS Number
97501-92-3
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