MC-VC-PABC-C6-α-Amanitin
MC-VC-PABC-C6-α-Amanitin is a Drug-Linker Conjugates for ADC, consisting of an anticancer toxin alpha-Amanitin and a MC-VC-PABC-C6 linker. Among them, alpha-Amanitin is a potent inhibitor of RNA polymerase IIα.
Product Specifications
CAS Number
2922514-69-8
UNSPSC
12352203
Target
Drug-Linker Conjugates for ADC
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mc-vc-pabc-c6-alpha-amanitin.html
Purity
98.88
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=[S@](C[C@@](NC(CNC([C@@]([C@@H](C)CC)([H])N1)=O)=O)([H])C(N[C@@](C(N(C[C@H](O)C2)[C@]2([H])C3=O)=O)([H])CC(N)=O)=O)C4=C(C[C@](C(NCC1=O)=O)([H])NC([C@](N3)([H])[C@@H](C)[C@@H](O)CO)=O)C5=CC=C(OCCCCCCNC(OCC6=CC=C(NC([C@@H](CCCNC(N)=O)NC([C@@H](C(C)C)NC(CCCCCN7C(C=CC7=O)=O)=O)=O)=O)C=C6)=O)C=C5N4
Molecular Formula
C74H105N17O22S
Molecular Weight
1616.79
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Daunorubicins/Doxorubicins
Available Sizes
Frequently Asked Questions
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