Muscotoxin A
Muscotoxin A is an ADC cytotoxin. Muscotoxin A is a cytotoxic lipopeptide that permeabilizes mammalian cell membranes and induces necrotic cell death[1].
Product Specifications
CAS Number
1653999-47-3
UNSPSC
12352203
Target
ADC Payload
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/muscotoxin-a.html
Solubility
10 mM in DMSO
Smiles
O=C(N1CCC[C@]1(C(NC(CC(CCCCC)O)C(O)C(N[C@H](CCC(N)=O)C(NCC(N2CCC[C@]2(C(N[C@H]3CC4=CC=CC=C4)=O)[H])=O)=O)=O)=O)[H])[C@@]([H])([C@H](CC)C)NC([C@H](CO)NC(/C(NC([C@H](CO)NC([C@@]([H])([C@H](CC)C)NC3=O)=O)=O)=C/C)=O)=O
Molecular Formula
C58H90N12O16
Molecular Weight
1211.41
References & Citations
[1]Petr Tomek, et al. Cytotoxic Lipopeptide Muscotoxin A, Isolated From Soil Cyanobacterium Desmonostoc Muscorum, Permeabilizes Phospholipid Membranes by Reducing Their Fluidity. Chem Res Toxicol. 2015 Feb 16;28 (2) :216-24.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Frequently Asked Questions
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