Mytoxin B
Mytoxin B is an ADC cytotoxin. Mytoxin B is a satratoxin-type trichothecene macrolide and is similar to the effect of LY294002. Mytoxin B induces cell apoptosis via PI3K/Akt pathway[1].
Product Specifications
CAS Number
105049-15-8
UNSPSC
12352005
Target
ADC Payload; Apoptosis; PI3K
Type
Natural Products
Related Pathways
Antibody-drug Conjugate/ADC Related; Apoptosis; PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mytoxin-b.html
Solubility
10 mM in DMSO
Smiles
CC1=C[C@](O[C@H]2[C@]3(OC3)[C@]4(C)[C@@H](C2)OC(/C=C/CC[C@@]5(C(C)=O)OCC/C([C@H]5O)=C/C(OC6)=O)=O)([H])[C@]46CC1
Molecular Formula
C29H36O9
Molecular Weight
528.59
References & Citations
[1]Huiliang Song, et al. Mytoxin B and Myrothecine A Induce Apoptosis in Human Hepatocarcinoma Cell Line SMMC-7721 via PI3K/Akt Signaling Pathway. Molecules. 2019 Jun 20;24 (12) :2291.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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