MDNI-caged-L-glutamate
MDNI-caged-L-glutamate (MDNI-glu) is a biologically inert, photosensitive derivative of the major excitatory amino acid, L-glutamate. MDNI-caged-L-glutamate makes more efficient use of incident light[1].
Product Specifications
CAS Number
864085-92-7
Product Name Alternative
MDNI-glu
UNSPSC
12352005
Target
Amino Acid Derivatives
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/mdni-caged-l-glutamate.html
Solubility
10 mM in DMSO
Smiles
O=C(O)[C@@H](N)CCC(N1CCC2=C1C([N+]([O-])=O)=CC([N+]([O-])=O)=C2OC)=O
Molecular Formula
C14H16N4O8
Molecular Weight
368.30
References & Citations
[1]Olesya D Fedoryak, et al. Synthesis of a caged glutamate for efficient one- and two-photon photorelease on living cells. Chem Commun (Camb) . 2005 Aug 7; (29) :3664-6.|[2]Papageorgiou G, Ogden D, Kelly G, Corrie JE. Synthetic and photochemical studies of substituted 1-acyl-7-nitroindolines. Photochem Photobiol Sci. 2005;4 (11) :887-896. |[3]Morgante P, Guruge C, Ouedraogo YP, Nesnas N, Peverati R. Competition between cyclization and unusual Norrish type I and type II nitro-acyl migration pathways in the photouncaging of 1-acyl-7-nitroindoline revealed by computations. Sci Rep. 2021;11 (1) :1396.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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