IHR-Cy3
IHR-Cy3 is a potent fluorescent Smo antagonist with an IC50 of 100 nM[1].
Product Specifications
UNSPSC
12352005
Target
Smo
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ihr-cy3.html
Solubility
10 mM in DMSO
Smiles
ClC1=CC=C(C(C(NC2=CC=C(C=C2)NC(C3=C(C=CC(NC(CCCCCCNC(CCCCC[N+]4=C(C(C)(C5=C4C=CC(S(=O)(O)=O)=C5)C)/C=C/C=C6N(C7=C(C/6(C)C)C=C(S(=O)([O-])=O)C=C7)CC)=O)=O)=C3)Cl)=O)=O)=C1)Cl
Molecular Formula
C58H63Cl3N6O10S2
Molecular Weight
1174.64
References & Citations
[1]Chih-Wei Fan, et al. The Hedgehog Pathway Effector Smoothened Exhibits Signaling Competency in the Absence of Ciliary Accumulation. Chem Biol
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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