IHR-Cy3
Product Specifications
UNSPSC Description
IHR-Cy3 is a potent fluorescent Smo antagonist with an IC50 of 100 nM[1].
Target Antigen
Smo
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ihr-cy3.html
Solubility
10 mM in DMSO
Smiles
ClC1=CC=C(C(C(NC2=CC=C(C=C2)NC(C3=C(C=CC(NC(CCCCCCNC(CCCCC[N+]4=C(C(C)(C5=C4C=CC(S(=O)(O)=O)=C5)C)/C=C/C=C6N(C7=C(C/6(C)C)C=C(S(=O)([O-])=O)C=C7)CC)=O)=O)=C3)Cl)=O)=O)=C1)Cl
Molecular Weight
1174.64
References & Citations
[1]Chih-Wei Fan, et al. The Hedgehog Pathway Effector Smoothened Exhibits Signaling Competency in the Absence of Ciliary Accumulation. Chem Biol
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-131016/IHR-Cy3-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-131016/
Clinical Information
No Development Reported
Curated Selection
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