FFN270 (hydrochloride)

FFN270 hydrochloride, a fluorescent tracer of norepinephrine, is a fluorescent substrate of the norepinephrine and vesicular monoamine transporters. FFN270 hydrochloride exhibits two resolved absorption/excitation maxima depending on solvent pH (FFN270 ex: 320 nm or 365 nm, em: 475 nm) and can function as ratiometric fluorescent pH-sensors[1].

Product Specifications

CAS Number

[2341841-05-0]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Adrenergic Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/ffn270-hydrochloride.html

Purity

99.0

Solubility

10 mM in DMSO

Smiles

O=C1C(CCN)=CC2=CC=C(O)C(F)=C2O1.[H]Cl

Molecular Formula

C11H11ClFNO3

Molecular Weight

259.66

Precautions

H302, H315, H319, H335

References & Citations

[1]Matthew Dunn, et al. Designing a norepinephrine optical tracer for imaging individual noradrenergic synapses and their activity in vivo. Nat Commun. 2018 Jul 19;9 (1) :2838.