N-Boc-Val-Dil-Dap-Doe
Product Specifications
UNSPSC Description
N-Boc-Val-Dil-Dap-Doe is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Target Antigen
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/n-boc-val-dil-dap-doe.html
Solubility
10 mM in DMSO
Smiles
CC([C@H](NC(OC(C)(C)C)=O)C(N([C@H]([C@@H](CC(N1[C@@H](CCC1)[C@@H]([C@H](C(N[C@@H](CC2=CC=CC=C2)C3=NC=CS3)=O)C)OC)=O)OC)[C@@H](C)CC)C)=O)C
Molecular Weight
758.02
References & Citations
[1]Céline Mordant, et al. Total synthesis of dolastatin 10 through ruthenium-catalyzed asymmetric hydrogenations. Tetrahedron. Volume 63, Issue 27, 2 July 2007, Pages 6115-6123.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-130976/N-Boc-Val-Dil-Dap-Doe-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-130976/
Clinical Information
No Development Reported
CAS Number
135383-62-9
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