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Boc-Val-Dil-Dap-Phe-OMe

Boc-Val-Dil-Dap-Phe-OMe is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].

Product Specifications

CAS Number

1415246-55-7

UNSPSC

12352203

Hazard Statement

H302-H315-H319-H335

Target

ADC Linker

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/boc-val-dil-dap-phe-ome.html

Solubility

10 mM in DMSO

Smiles

CC([C@H](NC(OC(C)(C)C)=O)C(N([C@H]([C@@H](CC(N1[C@@H](CCC1)[C@@H]([C@H](C(N[C@@H](CC2=CC=CC=C2)C(OC)=O)=O)C)OC)=O)OC)[C@@H](C)CC)C)=O)C

Molecular Formula

C39H64N4O9

Molecular Weight

732.95

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Céline Mordant, et al. Total synthesis of dolastatin 10 through ruthenium-catalyzed asymmetric hydrogenations. Tetrahedron. Volume 63, Issue 27, 2 July 2007, Pages 6115-6123.

Shipping Conditions

Room temperature

Scientific Category

ADC Related

Clinical Information

No Development Reported

Isoform

Cleavable Linker

Frequently Asked Questions

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