Ald-Ph-PEG4-bis-PEG4-propargyl
Product Specifications
UNSPSC Description
Ald-Ph-PEG4-bis-PEG4-propargyl is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Ald-Ph-PEG4-bis-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Target Antigen
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ald-ph-peg4-bis-peg4-propargyl.html
Solubility
10 mM in DMSO
Smiles
O=C(CCOCCOCCOCCOCCNC(C1=CC=C(C=O)C=C1)=O)NC(COCCC(NCCOCCOCCOCCOCC#C)=O)COCCC(NCCOCCOCCOCCOCC#C)=O
Molecular Weight
1041.19
References & Citations
[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-130967/Ald-Ph-PEG4-bis-PEG4-propargyl-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-130967/
Clinical Information
No Development Reported
Curated Selection
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