Tubulysin IM-2
Tubulysin IM-2 is a microtubule/Tubulin inhibitor that can act as an ADC cytotoxin (ADC Cytotoxin) and an anti-microtubule toxin (anti-microtubule toxins) . Used for ADC synthesis.
Product Specifications
CAS Number
1032072-50-6
UNSPSC
12352203
Target
ADC Payload; Microtubule/Tubulin
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tubulysin-im-2.html
Solubility
10 mM in DMSO
Smiles
CN1CCCC[C@@H]1C(N[C@H](C(N([C@H](C[C@H](C2=NC(C(O)=O)=CS2)OC(C)=O)C(C)C)C)=O)[C@H](CC)C)=O
Molecular Formula
C26H42N4O6S
Molecular Weight
538.70
References & Citations
[1]EGFR ANTIBODY-BASED COMBINATION THERAPY. Oct 30, 2015
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Traditional Cytotoxic Agents
Frequently Asked Questions
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