Tubulysin IM-1
Tubulysin IM-1 is a microtubule/Tubulin inhibitor that can act as an ADC cytotoxin (ADC Cytotoxin) and an anti-microtubule toxin (anti-microtubule toxins) . Used for ADC synthesis[1].
Product Specifications
UNSPSC
12352203
Target
ADC Payload; Microtubule/Tubulin
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tubulysin-im-1.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CSC([C@@H](C[C@@H](N(C(OC(C)(C)C)=O)C)C(C)C)OC(C)=O)=N1)N[C@H](C[C@H](C)C(CC)=O)CC2=CC=CC=C2
Molecular Formula
C32H47N3O6S
Molecular Weight
601.80
References & Citations
[1]EGFR ANTIBODY-BASED COMBINATION THERAPY. Oct 30, 2015
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Traditional Cytotoxic Agents
Frequently Asked Questions
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