Fmoc-Ala-Ala-Asn (Trt) -OH
Fmoc-Ala-Ala-Asn (Trt) -OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].
Product Specifications
CAS Number
[1951424-92-2]
UNSPSC
12352203
Hazard Statement
H302, H315, H319, H335
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fmoc-ala-ala-asn-trt-oh.html
Purity
99.80
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
OC([C@@H](NC([C@@H](NC([C@@H](NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)C)=O)C)=O)CC(NC(C4=CC=CC=C4)(C5=CC=CC=C5)C6=CC=CC=C6)=O)=O
Molecular Formula
C44H42N4O7
Molecular Weight
738.83
Precautions
H302, H315, H319, H335
References & Citations
[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16 (5) :315-337.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, stored under nitrogen, away from moisture)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Cleavable Linker
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