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Dihydrodeoxyuridine

Dihydrodeoxyuridine (H2dUrd) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Product Specifications

CAS Number

[5626-99-3]

Product Name Alternative

H2dUrd

UNSPSC

12352005

Hazard Statement

H315, H319, H320

Target

Nucleoside Antimetabolite/Analog

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/dihydrodeoxyuridine.html

Purity

98.71

Solubility

H2O : 125 mg/mL (ultrasonic)

Smiles

O=C1NC(CCN1[C@H]2C[C@H](O)[C@@H](CO)O2)=O

Molecular Formula

C9H14N2O5

Molecular Weight

230.22

Precautions

H315, H319, H320

References & Citations

[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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