Dihydrodeoxyuridine
Dihydrodeoxyuridine (H2dUrd) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
CAS Number
[5626-99-3]
Product Name Alternative
H2dUrd
UNSPSC
12352005
Hazard Statement
H315, H319, H320
Target
Nucleoside Antimetabolite/Analog
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dihydrodeoxyuridine.html
Purity
98.71
Solubility
H2O : 125 mg/mL (ultrasonic)
Smiles
O=C1NC(CCN1[C@H]2C[C@H](O)[C@@H](CO)O2)=O
Molecular Formula
C9H14N2O5
Molecular Weight
230.22
Precautions
H315, H319, H320
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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