5-Aminouridine

5-Aminouridine can modify nucleobases and can be incorporated into the target DNA. 5-Aminouridine exhibits a wide range of biological activity and it inhibits the growth of tumors, fungi and viruses[1][2].

Product Specifications

CAS Number

[2149-76-0]

UNSPSC

12352005

Target

Fungal; Influenza Virus

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/5-aminouridine.html

Purity

99.31

Solubility

10 mM in DMSO

Smiles

OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N(C(N2)=O)C=C(N)C2=O)O1

Molecular Formula

C9H13N3O6

Molecular Weight

259.22

References & Citations

[1]Smith DA, et al. Studies on 5-aminouridine. Biochim Biophys Acta. 1966 May 19;119 (2) :221-8.|[2]ROBERTS M, et al. Antimetabolite activity of uridine and cytidine derivatives. J Biol Chem. 1952 Feb;194 (2) :695-701. PMID: 14927662.. . .|[3]MR, et al. Detection of attomole quantities [correction of quantitites] of DNA targets on gold microelectrodes by electrocatalytic nucleobase oxidation. Anal Chem. 2003 Dec 1;75 (23) :6586-92.