NH2-C2-amido-C2-Boc
Product Specifications
UNSPSC Description
NH2-C2-amido-C2-Boc is a PROTAC linker, which refers to the alkyl/ether composition. NH2-C5-NH-Boc can be used in the synthesis of a series of PROTACs, such as the PROTAC CDK2/9 Degrader-1 (HY-130709)[1].
Target Antigen
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nh2-c2-amido-c2-boc.html
Solubility
10 mM in DMSO
Smiles
O=C(OC(C)(C)C)CCC(NCCN)=O
Molecular Weight
216.28
References & Citations
[1]Zhou F, et al. Development of selective mono or dual PROTAC degrader probe of CDK isoforms. Eur J Med Chem. 2019 Dec 6;187:111952.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-130712/NH2-C2-amido-C2-Boc-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-130712/
Clinical Information
No Development Reported
CAS Number
1692613-62-9
Curated Selection
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