PD 127443
Product Specifications
UNSPSC Description
PD 127443 is an inhibitor of 5-lipoxygenase and cyclooxygenase. PD 127443 has anti-inflammatory activity[1].
Target Antigen
COX; Lipoxygenase
Type
Reference compound
Related Pathways
Immunology/Inflammation;Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/pd-127443.html
Smiles
OC1=C(C=C(C=C1C(C)(C)C)/C=C/C2=NNC(C)=C2)C(C)(C)C
Molecular Weight
312.45
References & Citations
[1]Schrier DJ, et al. The in vivo antiinflammatory effects of (E)-2,6-bis(1,1-dimethyl-ethyl)-4-[2-(5-methyl-1H-pyrazol-3-yl)ethenyl ] phenol (PD 127443) a novel dual inhibitor of 5-lipoxygenase and cyclooxygenase. Agents Actions. 1989 Jun;27(3-4):391-4.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-123391/PD-127443-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-123391/
Clinical Information
No Development Reported
CAS Number
121502-05-4
Curated Selection
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