What is the catalog number for PERK-IN-3?

The catalog number for PERK-IN-3 is HY-130643.

What sizes are available for PERK-IN-3?

PERK-IN-3 is available in the following size(s): 1 Each.

Is PERK-IN-3 in stock?

PERK-IN-3 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PERK-IN-3?

PERK-IN-3 is manufactured by QuantiMol.

What is the estimated delivery time for PERK-IN-3?

Estimated delivery time for PERK-IN-3 is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for PERK-IN-3?

The safety data sheet for PERK-IN-3 is available here: http://file.medchemexpress.com/batch_PDF/HY-130643/.

PERK-IN-3

PERK-IN-3 is a potent PERK inhibitor with an IC50 of 7.4 nM[1].

Product Specifications

CAS Number

1337532-08-7

UNSPSC

12352005

Target

PERK

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/perk-in-3.html

Solubility

10 mM in DMSO

Smiles

FC1=CC=C(F)C(CC(N2CCC3=C2C=CC(C4=COC5=NC=NC(N)=C54)=C3)=O)=C1

Molecular Formula

C22H16F2N4O2

Molecular Weight

406.38

References & Citations

[1]Axten JM , et al. Discovery of 7-methyl-5- (1-{[3- (trifluoromethyl) phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl) -7H-pyrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a potent and selective first-in-class inhibitor of protein kinase R (PKR) -like endoplasmic reticulum kinase (PERK) . J Med Chem. 2012 Aug 23;55 (16) :7193-207.