(S,R,S)-AHPC-O-Ph-PEG1-NH-Boc
Product Specifications
UNSPSC Description
(S,R,S)-AHPC-O-Ph-PEG1-NH-Boc (VH032-O-Ph-PEG1-NH-Boc) is a synthesized E3 ligase ligand-linker conjugate which is used for the EED-targeted PROTAC[1].
Target Antigen
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/s-r-s-ahpc-o-ph-peg1-nh-boc.html
Solubility
10 mM in DMSO
Smiles
CC(C)([C@H](NC(COC1=CC=C(OCCNC(OC(C)(C)C)=O)C=C1)=O)C(N2[C@@H](C[C@H](C2)O)C(NCC3=CC=C(C=C3)C4=C(N=CS4)C)=O)=O)C
Molecular Weight
723.88
References & Citations
[1]Hsu JH, et al. EED-Targeted PROTACs Degrade EED, EZH2, and SUZ12 in the PRC2 Complex. Cell Chem Biol. 2019 Nov 26.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-130638/S-R-S-AHPC-O-Ph-PEG1-NH-Boc-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-130638/
Clinical Information
No Development Reported
CAS Number
2409007-40-3
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