SHP2-IN-5
SHP2-IN-5 (compound 1) is an inhibitor of SHP2 (IC50: 97 nM) . SHP2 is a non-receptor protein tyrosine phosphatase associated with cell growth and proliferation. SHP2-IN-5 has the potential to inhibit cancer and SHP2-related human diseases[1].
Product Specifications
CAS Number
[54755-93-0]
UNSPSC
12352005
Target
SHP2
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/shp2-in-5.html
Solubility
10 mM in DMSO
Smiles
OC1=CC=C(C=C(C(O)=O)C=C(O)C2=O)C2=C1O
Molecular Formula
C12H8O6
Molecular Weight
248.19
References & Citations
[1]Kim B, et al. Development and structure-activity relationship study of SHP2 inhibitor containing 3, 4, 6-trihydroxy-5-oxo-5H-benzo [7] annulene[J]. Bioorganic & Medicinal Chemistry Letters, 2020, 30 (1) : 126756.. . .
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-130631/SHP2-IN-5-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-130631/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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