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ReAsH-EDT2

ReAsH-EDT2 is a red fluorescent dye that marks proteins. ReAsH-EDT2 is a membrane-permeable biarsenical compound that binds covalently to tetracysteine sequences which allows the protein to be imaged. ReAsH-EDT2 can be used for protein localization and trafficking. (λex=530 nm, λem=592 nm) [1][2].

Product Specifications

CAS Number

[438226-89-2]

UNSPSC

12171500

Hazard Statement

H301, H312, H330, H410

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/reash-edt2.html

Purity

95.0

Solubility

10 mM in DMSO

Smiles

O=C1C=CC2=NC3=C(C([As]4SCCS4)=C(O)C=C3)OC2=C1[As]5SCCS5

Molecular Formula

C16H13As2NO3S4

Molecular Weight

545.38

Precautions

H301, H312, H330, H410

References & Citations

[1]Adams SR, et, al. Preparation of the membrane-permeant biarsenicals FlAsH-EDT2 and ReAsH-EDT2 for fluorescent labeling of tetracysteine-tagged proteins. Nat Protoc. 2008;3 (9) :1527-34.|[2]Perdios L, et, al. Time-resolved FRET reports FGFR1 dimerization and formation of a complex with its effector PLCγ1. Adv Biol Regul. 2016 Jan;60:6-13.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Dye Reagents

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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